toxicological effects of perfluoroalkyl and polyfluoroalkyl substances pdf

Toxicological Effects Of Perfluoroalkyl And Polyfluoroalkyl Substances Pdf

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Perfluoroalkyl and polyfluoroalkyl substances PFAS are found widespread in drinking water, foods, food packaging materials and other consumer products. Several PFAS have been identified as endocrine-disrupting chemicals based on their ability to interfere with normal reproductive function and hormonal signalling.

Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances

This book serves as a timely and comprehensive overview of the latest science for perfluoroalkyl and polyfluoroalkyl substances PFASs , covering the development of methods for assessing PFASs in biological fluids and tissues as well as the current knowledge regarding their toxicity to vertebrate organisms. Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances provides critical assessments of the most controversial topics surrounding toxicological evaluation of PFASs to give readers an expert perspective on the issues. Emphasis is placed on the integration of modes and mechanisms of action with functional endpoints that are relevant to human and wildlife health. This book will be a useful resource for toxicologists, environmental chemists, risk assessors, and researchers with an interest in the class of compounds known as perfluoroalkyl and polyfluoroalkyl substances. Skip to main content Skip to table of contents. Advertisement Hide. This service is more advanced with JavaScript available.

Per- and polyfluoroalkyl substances PFASs , also perfluorinated alkylated substances are synthetic organofluorine chemical compounds that have multiple fluorine atoms attached to an alkyl chain. As such, they contain at least one perfluoroalkyl moiety , —C n F 2n —. They are more effective at reducing the surface tension of water than comparable hydrocarbon surfactants. They include the perfluorosulfonic acids such as the perfluorooctanesulfonic acid PFOS and the perfluorocarboxylic acids such as the perfluorooctanoic acid PFOA. Fluorosurfactants can reduce the surface tension of water down to a value half of what is attainable by using hydrocarbon surfactants.

Per- and polyfluoroalkyl substances

It seems that you're in Germany. We have a dedicated site for Germany. This book serves as a timely and comprehensive overview of the latest science for perfluoroalkyl and polyfluoroalkyl substances PFASs , covering the development of methods for assessing PFASs in biological fluids and tissues as well as the current knowledge regarding their toxicity to vertebrate organisms. Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances provide critical assessments of the most controversial topics surrounding toxicological evaluation of PFASs to give readers an expert perspective on the issues. Emphasis is placed on the integration of modes and mechanisms of action with functional endpoints that are relevant to human and wildlife health. This book will be a useful resource for toxicologists, environmental chemists, risk assessors and researchers with an interest in the class of compounds known as perfluoroalkyl and polyfluoroalkyl substances.

Toxicological and Health Effects of Per- and Polyfluoroalklyl Substance (PFAS) Mixtures

Once production of your article has started, you can track the status of your article via Track Your Accepted Article. Help expand a public dataset of research that support the SDGs. Christopher Lau, Dr. Cynthia Rider and Dr. Dieter Schrenk.

This section provides reviews from a variety of sources on the toxicology human and ecological of PFASs. Individual specific studies are not called out but can be found in the extensive bibliographies of the resources listed. Data on the effects of PFOS in humans and animals demonstrate ready absorption of PFOS and distribution of the chemical throughout the body by noncovalent binding to serum albumin and other plasma proteins. In animal models, PFOS is detected predominantly in liver, serum, and kidney.

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